Publications – Dr. Jens Holz

75.Luehr S, Holz J, Odalys Z, Seidelmann O, Domke L, Boerner A TETRAHEDRON: ASYMMETRY 2013, 24, 395-401. Synthesis of Enantiopure ß2-homoalanine Derivatives via Rhodium Catalyzed Asymmetric Hydrogenation.
74.S. Luehr, J. Holz, O. Zayas, V. Wendisch, A. Boerner Tetrahedron: Asymmetry 2012, 23, 1301-1319. Synthesis of Chiral ß2-Amino acids by Asymmetric Hydrogenation
73.S. Luehr, J. Holz, A. Boerner Chem. Cat. Chem. 2011, 3, 1708-1730. The Synthesis of Chiral Phosphorus Ligands for use in Homogeneous Metal Catalysis.
72.B. Schaeffner, V. Andrushko, J. Bayardon, J. Holz, A. Boerner Chirality 2009, 21,  857-861. Organic carbonates as alternative solvents for asymmetric hydrogenation.
71.M. Sebek, J. Holz, Jens; A. Boerner,K. Jaehnisch Synlett 2009, 461-465. Highly diastereoselective hydrogenation of furan-2-carboxylic acid derivatives on heterogeneous catalysts.
70.J. Holz. B. Schaeffner, O. Zayas, A. Spannenberg, A. Boerner Adv. Synth. Catal. 2008, 350, 2533-2543. Synthesis of chiral 2-hydroxy-1-methylpropanoates by rhodium-catalyzed stereoselective hydrogenation of a -(hydroxymethyl)-acrylate derivatives.
69.J. Holz, A. Boerner in Phosphorus Ligands in Asymmetric Synthesis, Ed.: A. Boerner, Wiley-VCH Verlag, Weinheim, 2008, 2, 809-827. Chiral Polyphosphorus Ligands.
68.B. Schaeffner, V. Andrushko, J. Holz, S. P. Verevkin, A. Boerner ChemSusChem 2008, 1, 934-40. Rh-catalyzed asymmetric hydrogenation of unsaturated lactate precursors in propylene carbonate.
67.R. Kadyrov, J. Holz, B. Schaeffner, O. Zayas, J. Almena, A. Boerner, Tetrahedron: Asymmetry 2008, 19, 1189-1192. Synthesis of chiral b -aminophosphonates via Rh-catalyzed asymmetric hydrogenation of b -amido-vinylphosphonates.
66.B. Schaeffner, J. Holz, S. P. Verevkin, A. Boerner, ChemSusChem 2008, 1, 249-253. Organic carbonates as alternative solvents for palladium-catalyzed substitution reactions.
65.B. Schaeffner, J. Holz, S. P. Verevkin, A. Boerner, Tetrahedron Letters 2008, 49, 768-771. Rhodium-catalyzed asymmetric hydrogenation with self-assembling catalysts in propylene carbonate.
64.I. D. Kostas, K. A. Vallianatou, J. Holz, A. Boerner, Tetrahedron Letters 2008, 49, 331-334. A new easily accessible chiral phosphite-phosphoramidite ligand based on 2-anilinoethanol and R-BINOL moieties for Rh-catalyzed asymmetric olefin hydrogenation.
63.J. Holz, A. Boerner, D. Heller, H.-J. Drexler, Z. Kristallogr NCS. 2007, 222, 463-464. ”Crystal structure of (2,3-bis((2R,5R)-2,5-dimethylphosphonalyl)maleic anhydride)-(h4-norbornadiene)-rhodium(I) tetrafluoroborate, [Rh(C7H8)(C16H24O3P2)][BF4]”.

M.-N. Birkholz, N. V. Dubrovina, I. A. Shuklov, J. Holz, R. Paciello, C. Waloch, B. Breit, A. Boerner, Tetrahedron: Asymmetry 2007, 18, 2055-2060, Enantioselective Pd-catalyzed allylic amination with self-assembling and non-assembling monodentate phosphine ligands.


J. Bayardon, J. Holz, B. Schaeffner, V. Andrushko, S. Verevkin, A. Preetz, A. Boerner, Angew. Chem., Intern. Ed. 2007, 46, 5971-5974, Propylene carbonate as a solvent for asymmetric hydrogenations.


T. H. Riermeier, A. Monsees, J. Holz, A. Boerner, J. Tarabocchia, Chemical Industries (Boca Raton, FL, United States) 2007, 115, 455-461, catASium M: a new family of chiral bisphospholanes and their application in enantioselective hydrogenations.


I. Karame, E. Bellur, S. Rotzoll, P. Langer, C. Fischer, J. Holz, A. Boerner, Synth.

Commun. 2007, 37, 1067-1076. Highly enantioselective hydrogenation of b -alkyl and b -(w -chloroalkyl) substituted b -keto esters.

S. Enthaler, G. Erre, K. Junge, J. Holz, A. Boerner, E. Alberico,I. Nieddu, S. Gladiali, M. Beller, Org. Proc. Res. & Develop. 2007, 11, 568-577, Development of practical rhodium phosphine catalysts for the hydrogenation of b-dehydroamino acid derivatives.


M.-N. Birkholz; N. V. Dubrovina; H. Jiao; D. Michalik; J. Holz; R. Paciello; B. Breit; A. Börner, Chem. Eur. J. 2007, 13,

5896-5907. Enantioselective Hydrogenation with Self-Assembling Rhodium Phosphane Catalysts: Influence of Ligand Structure and Solvent.

J. Holz, A. Monsees, R. Kadyrov, A. Boerner, Synlett 2007, 599-602. Chiral P-chlorophospholane: A Versatile Building Block for the Synthesis of Ligands.


J. Holz, M.-N. Gensow, O. Zayas, A. Börner, Current Organic Chemistry 2007, 11, 61-106. Synthesis of Chiral Heterocyclic Phosphines for Application in Asymmetric Catalysis.


K. A. Vallianatou, <st1:place w:st="on">I.</st1:place> D. Kostas, J. Holz, A. Boerner, Tetrahedron Lett. 2006, 47, 7947-7950. Me-AnilaPhos, a New Chiral Phosphine-Phosphoramidite Ligand for a Highly Efficient Rh-catalyzed Asymmetric Olefin Hydrogenation.


J. Holz, O. Zayas, H. Jiao, W. Baumann, A. Spannenberg, A. Monsees, T. H. Riermeier, J. Almena, R. Kadyrov, A. Börner, Chem. Eur. J. 2006, 12, 5001-5013. A Highly Tunable Bisphospholanes for the Rh-Catalyzed Enantioselective Hydrogenation Reactions.


I. D. Kostas, K. A. Vallianatou, J. Holz, A. Börner, Appl. Organomet. Chem. 2005, 19, 1090-1095. Rhodium Complexes with a new Chiral Nitrogen-containing BINOL-based Diphosphite or Phosphonite Ligand. Synthesis and Application to Hydroformylation of Styrene and/or Hydrogenation of Prochiral Olefins.


A. Börner, J. Holz, Olefin Hydrogenation, in Transition Metals for Fine Chemicals and Organic Synthesis, Hrsg. M. Beller, C. Bolm, VCH-Wiley, Vol. II, 2. Auflage, Weinheim 2004, Vol. 2, S. 3.


J. Almena, A. Monsees, R. Kadyrov, T. H. Riermeier, B. Gotov, J. Holz, A. Börner, Adv. Synth. Catal. 2004,346, 1263-1266. Asymmetric Hydrogenation of Itaconic Acid Derivatives with the New CatASium® M Catalysts.


J. Holz, A. Börner, A. Spannenberg, C. Pribbenow, D. Heller, H.-J. Drexler, Z. Kristall. NCS 2004, 219, 199-200. Crystal Structure of (η4-norbona-2,5-dien)-(1,2-bis((R,R)-2,5-bis-(methoxymethyl)phopholanyl)benzene)rhodium(I) Tetrafluoroborate, [Rh(C22H36O4P2)(C7H8)](BF4).


T. H. Riermeier, A. Monsees, J. Holz, A. Börner, Chimia Oggi, 2004, 22-24. catASium®M - A New Family of Chiral Bisphospholanes and Their Application in Enantioselective Hydrogenations.


I. V. Komarov,  A. Spannenberg, J. Holz, A. Börner, Chem. Commun. 2003, 2240-2241. Highly Stereoselective, Thermodynamically Controlled and Reversible Formation of a new P-chiral Phosphine.


J. Holz, A. Monsees, H. Jiao, J. You, I. V. Komarov, C. Fischer,  K. Drauz, A. Börner, J. Org. Chem. 2003, 1701-1707. Synthesis of a New Chiral Bisphospholane Ligand for the Rh(I) Catalyzed Enantioselective Hydrogenation of Isomeric β-Acylamido Acrylates.


D. Heller, J. Jolz, I. Komarov, H.-J. Drexler, J. You, K. Drauz, A. Börner, Tetrahedron: Asymmetry 2002, 13, 2735-2741. On the Enantioselective Hydrogenation of Isomeric β-Acylamido β-Alkylacrylates with Chiral Rh(I) Complexes – Comparison of Phosphine Ligands and Substrates.


J. Holz, A. Börner, (S,S)-Ethyl-DuPHOS, e-EROS, Encyclopedia of Reagents for Organic Synthesis, Wiley, Chichester, 2001.


J. Holz, R. Stürmer, U. Schmidt, H.-J. Drexler, D. Heller, H.-P. Krimmer, A. Börner Eur. J. Org. Chem. 2001, 4615-4624. Synthesis of Chiral 2,5-Bis(oxymethyl)-functionalized Bis(phospholanes) and Their application in Rh- and Ru-catalyzed Enantioselective Hydrogenations.


V. Fehring, R. Kadyrov, M. Ludwig, J. Holz, K. Haage, R. Selke J. Organomet. Chem. 2001, 621, 120-129. Synthesis of Achiral, but Unsymmetric, Seven-membered Rhodium(I)-chelates for Hydrogenation in the Chiral Environment of Alkyl Polyglucoside Micelles.


D. Heller, J. Holz, H.-J. Drexler, J. Lang, H.-P. Krimmer, K. Drauz, A. Börner J. Org. Chem. 2001, 66, 6816-6817. Pressure Dependent Highly Enantioselective Hydro-genation of Unsaturated β-Amino Acid Precursors.


J. holz, R. Kadyrov, S. Borns, D. Heller, A. Börner J. Organomet. Chem. 2000, 603, 61-68. Cooperative Attractive Interactions in Asymmetric Hydrogenations with Dihydroxydiphosphine Rh(I) Catalysts – a Competition Study.


V. I. Tararaov, R. Kadyrov; T.H. Riermeier, J. Holz, A. Börner Tetrahedron Letters 2000, 41, 2351-2355. Rhodium(I) Catalyzed Asymmetric Hydrogenation of Enamines.


M. Quirmbach, J. Holz, V. I. Tararov, A. Börner Tetrahedron 2000, 56, 775-780. Synthesis of Heterofunctionalized Multidentate Diphosphines.


V. I. Tararov, R. Kadyrov, T. H. Riermeier, J. Holz, A. Börner Tetrahedron: Asymmetry 1999, 10, 4009-4015. Phosphines Versus Phosphinites as Ligands in the Rhodium Catalyzed Asymmetric Hydrogenation of Imines: a Systematic Study.


J. Holz, D. Heller, R. Stürmer, A. Börner Tetrahedron Letters 1999, 40, 7059-7062. Synthesis of the First Water-soluble Chiral Tetrahydroxy Diphosphine Rh(I) Catalyst for the Enantioselective Hydrogenation.


S. Borns, R. Kadyrov, D. Heller, W. Baumann, J. Holz, A. Börner, Tetrahedron: Asymmetry, 1999, 10, 1425-1431. Counter-ligand and Solvent Dependent Oxygen-metal Interactions of Hemilabile Coordinating Hydroxy Groups in Chiral Phosphine Rhodium(I) Hydrogenation Catalysts.


S. Trinkhaus, R. Kadyrov, J. Holz, R. Selke, L. Götze, A. Börner, J. Mol. Catal. A.: Chemical 1999, 144, 15-26. Internal Versus External Ionic Functionalities - A Comparative Study in the Asymmetric Hydrogenation in Water as Solvent.


J. Holz, M. Quirmbach, U. Schmidt, D. Heller, R. Stürmer, A. Börner, J. Org. Chem. 1998, 63, 8031-8034. Synthesis of a New Class of Functionalized Chiral Bisphospholane Ligands and the Application in Enantioselective Hydrogenations.


J. Holz, M. Quirmbach, L. Götze, A. Börner in Recent Research Developments in Organic Chemistry, Transworld Research Network, Trivandrum 1998, 2, 685-711. New Methodologies for the Construction of Chiral Hydroxy Phosphines.


M. Ohff, J. Holz, M. Quirmbach, A. Börner Synthesis 1998, 1391-1415. Borane-Complexes of Trivalent Organophosphorus Compounds - Versatile Precursors for the Synthesis of Chiral Phosphine Ligands for Asymmetric Catalysis.


S. Borns, R. Kadyrov, D. Heller, W. Baumann, A. Spannenberg, R. Kempe, J. Holz, A. Börner, Eur. J. Inorg. Chem. 1998, 1291-1295. Catalytic and Structural Features of Hydroxy and Methoxy Groups as Hemilabile Coordinating Ligands in Chiral Diphosphane Rhodium(I) Hydrogenation Catalysts.


R. Selke, J. Holz, A. Riepe, A. Börner, Chem. Eur. J. 1998, 769-771. Impressive Enhancement of the Enantioselectivity for a Hydroxy-Containing Rhodium(I) Bisphosphine Catalyst in Aqueous Solution by Micelle-forming Amphiphiles.


A. Börner, J. Holz, in Transition metals for Fine Chemicals and Organic Synthesis; Hrsg. M. Beller, C. Bolm, VCH 1998, Band II, 1-11. Olefin Hydrogenation.


A. Kless, J. Holz, H. Reinke, A. Börner, J. Organomet. Chem. 1997, 553, 99-102. Studies on the Formation of Uniform η3-coordinated Triphos-Mo(0)-Complexes.


J. Holz, M. Quirmbach, A. Börner, Synthesis 1997, 983-1006, Strategies for the Synthesis of Chiral Hydroxy Phosphines - A Class of Versatile Ligands and Ligand Precursors for Asymmetric Catalysis.


S. Trinkhaus, J. Holz, R. Selke, A. Börner, Tetrahedron Letters 1997, 38, 807-808. A Novel Method for the Synthesis of Chiral Sulfonated Phosphines.


D. Heller, J. Holz, S.Borns, A. Spannenberg, R. Kempe, U. Schmidt, A. Börner, Tetrahedron: Asymmetry 1997, 8, 213-222. Influence of a Remote Hydroxy Group in the Ligand on the Reactivity of a Chiral Hydrogenation Catalyst.


A. Kless, C. Lefeber, A. Spannenberg, R.Kempe, W. Baumann, J. Holz, A. Börner, Tetrahedron 1996, 52, 14599-14606. The First Chiral Early-Late Heterobimetallic Complex - A Titanium(IV)-Palladium(II) Complex Based on Salenophos.


J. Holz, A. Kless, A. Börner, Synlett 1996, 6, 267-269. An Efficient Strategy for the Synthesis of Chiral and Prochiral Triphosines.


A. Kless, J. Holz, D. Heller, R. Kadyrov, R. Selke, Ch. Fischer, A. Börner, Tetrahedron: Asymmetry 1996, 7, 33-36. Chiral Phosphinephosphites Having Centers of Axial and Central Chirality in Asymmetric Hydroformylations.


A. Börner, Ch. Fischer, D. Heller, J. Holz, M. Schwarze, R. Selke, G. Oehme, Jahrbuch der Max-Planck-Gesellschaft 1994, Vandenhoeck & Ruprecht, Göttingen, 1995, 719. Influence of Achiral Modifiers at the Enantioselectivity of Chiral Catalysts.


A. Börner, J. Holz, A. Kless, D. Heller, GIT Fachz. Lab. 1995, 339, 1146. Synthese von HydroxyDIOP-liganden und ihre Anwendung in der Rhodium-katalysierten asymmetrischen Hydrierung.


J. Holz, A. Börner, A. Kless, S. Borns, S. Trinkhaus, R. Selke, D. Heller, Tetrahedron: Asymmetry 1995, 6, 1973-1988. Hydroxyalkylphosphines in Asymmetric Hydrogenations.


Börner, A. Kless, R. Kempe, D. Heller, J. Holz, W. Baumann, Chem Ber. 1995, 128, 767-773. b-Alkoxy- and β-Hydroxyalkylphosphanes as Ligands in the Stereoselective Hydrogenation - A Comparison.


A. Kless, R. Kadyrov, A. Börner, J. Holz, H. B. Kagan, Tetrahedron Lett. 1995, 36, 4601-4602. A New Chiral Multidentate Ligand for Asymmetric Catalysis.


Börner, A. Kless, J. Holz, W. Baumann, A. Tillack, R. Kadyrov, J. Organomet. Chem. 1995, 490, 213. Komplexierung von enantiomerenreinen cis- und trans-3-Diphenylphosphino-4-hydroxy-tetrahydrofuranen mit [Rh(COD)2]BF4.


Börner, J. Ward, W. Ruth, J. Holz, A. Kless, D. Heller, H. B. Kagan, Tetrahedron 1994, 50, 10419-10430. Synthesis and Catalytic Properties of an Acyclic Analogue of Hydroxy Norphos.


Börner, R. Kadyrov, M. Michalik, D. Heller, J. Organomet. Chem. 1994, 470, 237-242. Analogues of DIOP. Synthesis, Reactivity, and NMR Behaviour.


Börner, J. Holz, A. Kless, D. Heller, Jahrbuch der Max-Planck-Gesellschaft 1993, Vandenhoeck & Ruprecht, Göttingen, 1994, 697. Bimetallic Catalysis.


A. Börner, J. Holz, A. Kless, D. Heller, U. Berens, Tetrahedron Lett. 1994, 35, 6071-6074, Synthesis of an Optically Active Hydroxy Diphosphine, A New Ligand for Asymmetric Catalysis.


Börner, J. Holz, J. Ward, H.B. Kagan, J. Org. Chem. 1993, 58, 6814-6817, Concise Synthesis of Enantiomerically Pure cis- and trans-3-(Diphenylphosphino)-4-hydroxy-tetrahydrofurans.


Börner, J. Holz, H.B. Kagan, Tetrahedron Lett. 1993, 34, 5273-5276, New Chiral Building Blocks and their Application to the Construction of Chiral Aminoalcohols: Enantiomerically Pure cis- and trans-3-Mesyloxy-4-hydroxy Tetrahydrofurans.


R. Miethchen, H. Prade, J. Holz, K. Praefcke, D. Blunck, Chem. Ber. 1993, 126, 1707-1712; Flüssigkristalline Verbindungen, 79. Amphiphile Fluoroglucose- und Fluoroscyllitol Derivate.


R. Miethchen, M. Schwarze, J. Holz, Liquid Cryst. 1993, 15, 185-191, 6,6-Di-C-(n-alkyl)-D-galactopyranoses - A New Group of Liquid Crystalline Compounds Forming Columnar Phases.


R. Miethchen, J. Holz, H. Prade, Colloid Polym. Sci. 1993, 271, 404-409; Amphiphilic and Mesogenic Carbohydrates Part III. Synthesis and Thermal Behaviour of Di-O-(n-alkyl)- and Tri-O-(n-alkyl)-D-glucose Derivatives.


R. Miethchen, J. Holz, H. Prade, A. Liptak, Tetrahedron 1992, 48, 3061-3068, Amphiphilic and Mesogenic Carbohydrates Part II. Synthesis and Characterization of Mono-O-(n-alkyl)-D-glucopyranose Derivatives.


R. Miethchen, T. Gabriel, D. Peters, J. Holz, M. Michalik, Carbohydr. Res. 1991, 215, 331-336; Synthese tensioaktiver 3-O-Alkyl-α-D-glucopyranosylfluorides and 6-O-Alkyl-α-D-galactopyranosylfluoride.


R. Miethchen, G. Kolp, D. Peters, J. Holz, Z. Chem. 1990, 30, 56-57; Reaktion mit und in wasserfreiem Fluorwasserstoff; Selektive Synthesen von Glucosylfluoriden.


D. Peters, J. Holz, R. Miethchen, J. Fluorine Chem. 1990, 50, 217-228; Micellen in wasserfreiem Fluorwasserstoff V. Aggregation von amphiphilen Alkylammoniumfluoriden und tensioaktiven Monosacchariden.


R. Miethchen, J. Holz, D. Peters, Z. Chem. 1989, 29, 420-421; Micellen in wasserfreiem Fluorwasserstoff: II. Aggregation von acetylierten 3-O-(n-Alkyl)-Derivaten der D-Glucopyranose.

16.J. Holz, A. Börner, K. Rumpel; P-chirale Phosphinenliganden und deren Verwendung zur asymmetrischen Synthese; EP 16174225.9 (13.06.2016)
15.A. Börner, J. Holz, K. Rumpel; P-chiral phosphine lingands and use thereof for asymmetric Synthesis; EP 16168649.8 (06.05.2016)
14.A. Börner, J. Holz, (BASF), Verfahren zur Herstellung von Citronellal, DE 10201303563.9 (10.04.2013)
13.H. Mena, J. Holz, A. Börner, T. Tsujimoto, T. Kutsuna, N. Fushimi, (Mitsubishi), Method for producing aromatic polyalcohol, JP 2011-138509 (22.06.2011)

 J. Holz, A. Börner, W. Büschken, R. Franke, M. Becker, (Evonik), Vorrichtung und Verfahren für kontinuierliche Umsetzung einer Flüssigkeit mit einem Gas PARALLELISIERTE STRAHLSCHLAUFENREAKTOREN, DE 102008041652.5 (28.08.2008)



J. Holz, A. Börner, B. Schäffner, (Uhde AG), efficient and highly evantioselective Rh catalyzed hydrogluations of unsaturated lactate precursors with chiral biphospholanes as ligand, DE 602008022250.0 (30.06.2008


J. Holz, A. Börner, T. H. Riermeier, A. Monsees, R. Kadyrov, P. Almena, (Degussa AG), Halogenphospholane und deren Herstellung DE 102005053079.6 (04.11.2005).


J. Holz, O. Zayas, A. Börner, A. Monsees, T. H. Riermeier, R. Kadyrov, P. Almena, Elektronenarme Bisphospholanliganden und -katalysatoren (Degussa AG), DE 10 2005 014 054.8 (23.03.2005), WO 2006100165.


J. Holz, A. Börner, A. Monsees, T. H. Riermeier, R. Kadyrov, P. Almena, Unsymmetrisch substituierte Phospholankatalysatoren (Degussa AG), DE 10 2005 014 055.6 (23.03.2005), WO 2006100169 (23.03.2005).


Börner, J. Holz, T. Riermeier, A. Monsees, J. Almena (Degussa AG), (22.10.2004), Neue Bisphospholanliganden, DE 102004051456


J. Holz, A. Börner, A. Monsees, T. H. Riermeier, K. Drauz, I. Nagl, W. Zeiss, W. Meichelböck, B. Gotov, R. Kadyrov, P. Almena (Degussa AG), Verfahren zur Herstellung von Bisphospholanliganden (18.11.2003), DE 10353831;


J. Holz, A. Börner, A. Monsees, K. Drauz, R. Kadyrov, T. Riermeier, C. Schneider, Dingerdissen (Aventis R&T) DE 102 14 988.7 (04.04.2002), Bisphosphine als bidentate Liganden, WO 03084971


H.-P. Krimmer, K. Drauz, J. Lang, A. Börner, D. Heller, J. Holz (Degussa AG) DE 101 00 971.2 (11.01.2001), Verfahren zur Herstellung von enantiomeren-angereicherten ß-Aminosäuren


J. Holz, G. Voß, R. Stürmer, A. Börner, (BASF), DE 19824121 (29.05.1998),  Herstellung optisch aktiver Phospholane und ihre Anwendung in der asymmetrischen Katalyse

2.A. Börner, J. Holz, G. Voss, R. Stürmer, M. Klatt (BASF), Verfahren zur asymmetrische Hydrierung von β-Ketoestern, DE 19845517 (02.10.1998)


A. Börner, J. Holz, G. Voß, R. Stürmer (MPG/BASF), DE 19725796 (18.06.1997), Synthese eines neuen Ligandentyps für asymmetrische Katalysen