Redoxreactions
Dr. Kathrin Junge
The development of environmentally benign and efficient catalytic reactions is one of the major challenges in present chemical research while the search for cheap metal catalyst is focussed more and more. Actually the demand of new chiral ligands for catalytic applications in industry is continuously very high. So our group has involved ligand synthesis in the investigation of catalytic reactions like oxidations and hydrogenations which are relevant for industry.
Metal catalyzed oxidation reaction is one of the most important homogenous catalyzed reactions in chemical industry. Our ongoing interest is to develop novel catalytic systems which produce industrially interesting chemicals by oxidation methods using cost-effective and environmentally friendly oxidants like oxygen or hydrogen peroxide. Actually we investigate ruthenium- and iron-catalyzed epoxidations with hydrogen peroxide.
Also in the field of hydrogenation the usage of iron catalysts has a growing influence. So our group successfully adopted the application of novel ligand classes in iron-catalyzed reactions. Besides hydrogenation of C=C, C=N and C=O double bonds, we also work on transfer hydrogenation and hydrosilylation. These tests can be realized in a normal autoclave (Parr) or in three 8-fold reactorarrays for parallelscreening.
- X. Tong, M. Beller, M. K. Tse, J. Am. Chem. Soc. 2007, 129, 4906-4907; Palladium-catalyzed Oxido-Cyclization of 1,6-Enynes: A Convenient Synthesis to Bicyclo[3.1.0] Hexanes and Evidence for SN2 C-O Reductive Elimination from Alkyl-Pd(IV) Intermediate.
- F. G. Gelalcha, B. Bitterlich, A. Gopinathan, M.-K. Tse, M. Beller, Angew. Chem. Int. Ed. 2007, 46, 7293-7296; An Environmentally Benign Fe-catalyzed Asymmetric Epoxidation of Aromatic Alkenes using Hydrogen Peroxide.
- F. Shi, M. K. Tse, M.-M. Pohl, A. Brückner, S. Zhang, M. Beller, Angew. Chem. Int. Ed. 2007, 46, 8866-8868; Tuning catalytic activity between homogeneous Fe3+ ion and heterogeneous bulk Fe2O3: Nano-Fe2O3 as an auspicious catalyst for selective oxidations.
- N. S. Shaikh, S. Enthaler, K. Junge, M. Beller, Angew. Chem. Int. Ed. 2008, 47, 2497-2501; Iron-catalyzed Enantioselective Hydrosilylation of Ketones under Mild Conditions.
- S. Enthaler, K. Junge, M. Beller, Angew. Chem. Int. Ed. 2008, 47, 3317-3321; Sustainable Metal Catalysis with Iron – From Rust to a Rising Star?
